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Usefulness of office examination with narrow band imaging for the diagnosis of head and neck squamous cell carcinoma and follow‐up of premalignant lesions
Author(s) -
Vilaseca Isabel,
VallsMateus Meritxell,
Nogués Anna,
Lehrer Eduardo,
LópezChacón Mauricio,
AvilésJurado Francesc Xavier,
Blanch José Luis,
BernalSprekelsen Manuel
Publication year - 2017
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24849
Subject(s) - medicine , dysplasia , biopsy , radiology , carcinoma , basal cell , head and neck , pathology , surgery
Background The purpose of this study was to evaluate the value of narrow band imaging (NBI) examination in the office for the diagnosis and follow‐up of upper airway premalignant and malignant lesions. Methods Four hundred eighty lesions were evaluated with white light endoscopy (WLE) and NBI before a biopsy/excision. Additionally, 151 premalignant lesions were followed up without proven biopsy. Carcinoma‐free survival was calculated. The learning curve was analyzed. Results Overall, the accuracy improved from 74.1% with WLE to 88.9% with NBI, being relevant in all anatomic subsites. The accuracy of NBI increased significantly with increasing experience (area under the curve [AUC] >0.9). After a follow‐up of 25 months, 14 of 151 lesions (9.3%) converted into carcinoma. The 4‐year carcinoma‐free survival rate was 86.4%. The 4‐year carcinoma‐free survival rate differed significantly between lesions classified as benign/mild dysplasia versus those presenting as moderate/severe dysplasia (88.9% vs 73.5%; P = .018). Conclusion The NBI provided a greater accuracy than WLE and showed promising usefulness for the follow‐up of premalignant lesions.