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Systematic review of mammary analog secretory carcinoma of salivary glands at 7 years after description
Author(s) -
Khalele Bacem A.
Publication year - 2017
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24755
Subject(s) - acinic cell carcinoma , malignancy , salivary gland , pathology , nosology , medicine , immunohistochemistry , head and neck , carcinoma , oncology , biology , mucoepidermoid carcinoma , surgery
Background Mammary analog secretory carcinoma of the salivary glands (MASC SG ) is a newly introduced malignant tumor of the salivary glands. For decades, it has been confused with acinic cell carcinoma (ACC) of the salivary glands. Methods All reported cases of MASC SG were surveyed from 2010 until January 2017. The collected data was compiled and computationally processed to describe the clinical parameters of MASC SG . Its epidemiology was also mapped. Moreover, inaccurate data was highlighted. Results Clinically implicating, this article tackles simply the several clinical findings of MASC SG so that our contemporary nosology, at 7 years after description, can be updated. The cytogenetic, histologic, and immunohistochemical details are also defined. Conclusion The available data about MASC SG is sufficient enough to diagnose it with no need to investigate the ETV6‐NTRK3 translocation. Although high‐grade malignancy and distant metastases were rarely reported, a rapt attention should be paid both to the nature of this tumor and to the indicated close follow‐up of such cases, especially when necrosis, increased mitotic activity, and other classic caveats are conspicuous. © 2017 Wiley Periodicals, Inc. Head Neck 39: 1243–1248, 2017