Premium
Cohort study of oncologic emergencies in patients with head and neck cancer
Author(s) -
Reyes–Gibby Cielito C.,
Melkonian Stephanie C.,
Hanna Ehab Y.,
Yeung Saiching J.,
Lu Charles,
Chambers Mark S.,
Banala Srinivas R.,
Gunn Gary B.,
Shete Sanjay S.
Publication year - 2017
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24748
Subject(s) - emergency department , medicine , head and neck squamous cell carcinoma , presentation (obstetrics) , cohort , cohort study , prospective cohort study , emergency medicine , head and neck cancer , cancer , surgery , psychiatry
Background Treatments for head and neck squamous cell carcinoma (HNSCC) are associated with toxicities that lead to emergency department presentation. Methods We utilized data from an ongoing prospective cohort of newly diagnosed, previously untreated patients ( N = 298) with HNSCC to evaluate the association between clinical and epidemiologic factors and risk for and frequency of emergency department presentation. Time to event was calculated from the date of treatment initiation to emergency department presentation, date of death, or current date. Frequency of emergency department presentation was the sum of emergency department visits during the follow‐up time. Results History of hypertension, normal/underweight body mass index (BMI), and probable depression predicted increased risk for emergency department presentation. BMI and severe pain were associated with higher frequency of emergency department presentations. Conclusion Clinical and epidemiologic factors can help predict patients with HNSCC who will present to the emergency department. Such knowledge may improve treatment‐related patient outcomes and quality of life. © 2017 Wiley Periodicals, Inc. Head Neck 39: 1195–1204, 2017