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Image‐guided interstitial high‐dose‐rate brachytherapy in the treatment of inoperable recurrent head and neck malignancies: An effective option of reirradiation
Author(s) -
Tselis Nikolaos,
Karagiannis Efstratios,
Kolotas Christos,
Baghi Mehran,
Milickovic Natasa,
Zamboglou Nikolaos
Publication year - 2017
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24697
Subject(s) - medicine , brachytherapy , head and neck cancer , nasal cavity , radiation therapy , radiology , paranasal sinuses , head and neck , lesion , surgery
Background In recurrent head and neck cancer, therapeutic options are limited and high‐quality evidence is rare. The purpose of this report was to present our experience of CT‐guided interstitial high‐dose rate (HDR) brachytherapy in 4 challenging cases of inoperable recurrent head and neck cancer. Methods A 53‐year‐old man with mucosal melanoma of the paranasal sinuses, a 61‐year‐old man with myofibroblastic sarcoma of the nasal cavity, a 51‐year‐old woman with nasopharyngeal cancer, and a 44‐year‐old woman with orbital leiomyosarcoma were treated with reirradiation by HDR brachytherapy after previous comprehensive therapy, including full course external radiotherapy (RT). Results All patients showed response to brachytherapy with 1 patient experiencing locoregional failure. The mean lesion‐specific disease control was 15 months. Currently, 1 patient is alive and 3 patients died after mean 20 months after treatment. Conclusion In patients with inoperable recurrent head and neck cancer, CT‐guided interstitial HDR brachytherapy can play a role in providing palliation and tumor control. © 2017 Wiley Periodicals, Inc. Head Neck 39: E61–E68, 2017