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Clinical impact of 18 F‐FDG positron emission tomography/CT on adenoid cystic carcinoma of the head and neck
Author(s) -
Jung Jihoon,
Lee SangWoo,
Son Seung Hyun,
Kim ChoonYoung,
Lee ChangHee,
Jeong Ju Hye,
Jeong Shin Young,
Ahn ByeongCheol,
Lee Jaetae
Publication year - 2017
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24605
Subject(s) - medicine , positron emission tomography , adenoid cystic carcinoma , nuclear medicine , standardized uptake value , radiology , head and neck , positron emission , pet ct , carcinoma , surgery
ABSTRACT Background The purpose of this retrospective study was to assess the diagnostic value of 18 F‐fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT and the prognostic value of metabolic PET parameters in patients with adenoid cystic carcinoma of the head and neck (ACCHN). Methods Forty patients with newly diagnosed ACCHN were enrolled in this study. We investigated the diagnostic value of 18 F‐FDG PET/CT for detecting and staging compared to conventional CT. Kaplan–Meier survival analysis for progression‐free survival (PFS) was performed with clinicopathological factors and metabolic PET parameters. Results The 18 F‐FDG PET/CT showed comparable sensitivity (92.3%) to conventional CT for lesion detection, and changed staging and management plan in 6 patients (15.0%). Lower PFS rates were associated with advanced T classification, advanced TNM classification, high maximum standardized uptake value (SUVmax; >5.1), and high total lesion glycolysis (>40.1) of the primary tumor. Conclusion The 18 F‐FDG PET/CT can provide additional information for initial staging, and metabolic PET parameters may serve as prognostic factors of ACCHN. © 2016 Wiley Periodicals, Inc. Head Neck 39: 447–455, 2017