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Recurrent giant mandibular ameloblastoma in young adults
Author(s) -
Gravvanis Andreas,
Koumoullis Harry D.,
Anterriotis Dimitrios,
Tsoutsos Dimosthenis,
Katsikeris Nick
Publication year - 2016
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24352
Subject(s) - medicine , ameloblastoma , swallowing , surgery , head and neck , mandible (arthropod mouthpart) , retrospective cohort study , radiological weapon , facial symmetry , dentistry , maxilla , botany , biology , genus
Background The purpose of the study was to define the most appropriate management of the giant mandibular ameloblastoma (GMA) in young adults. Methods A retrospective study was performed on patients with GMA <30 years old. The data collected included initial treatment, tumor margins, reconstruction, and follow‐up. Patients evaluated speech, chewing, swallowing, and facial appearance after definitive treatment. Results Thirteen patients were identified with recurrent solid/multicystic disease requiring further treatment. Definitive treatment involved segmental mandibulectomy and reconstruction with free fibular flap in all patients. Seven patients had immediate reconstruction (group A) and 6 had secondary (group B). Mandibular resection was planned at least 2 cm beyond the radiological limit, free margins were achieved in all patients, and all flaps were transplanted successfully. In group A, functional score was 13.7 ± 0.45 and facial appearance score was 4.5 ± 0.49, whereas in group B were 11.16 ± 0.37 and 3.3 ± 0.5, respectively (both p < .05). Conclusion Aggressive resection of the GMA and immediate reconstruction is strongly advised. © 2015 Wiley Periodicals, Inc. Head Neck 38 : E1947–E1954, 2016