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Possible esthesioneuroblastoma metastasis to paranasal sinuses: Clinical report and literature review
Author(s) -
Buohliqa Lamia,
Upadhyay Smita,
Nicolai Piero,
Cavalieri Robert,
Dolci Ricardo L. L.,
Prevedello Daniel,
Carrau Ricardo L.
Publication year - 2016
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24095
Subject(s) - esthesioneuroblastoma , paranasal sinuses , medicine , metastasis , radiology , cancer , radiation therapy
Background Local recurrence, and regional and distant metastases, respectively, develop in 30% and 15% of patients with esthesioneuroblastoma (ENB). Methods This case report includes 3 patients with unusual recurrences of ENB in the sinonasal tract. Results Patient 1 developed ENB in the bilateral maxillary sinuses after unilateral endoscopic resection of a left ENB followed by postoperative proton radiotherapy. Patient 2 developed ENB at the left optic‐carotid recess 7 years after a craniofacial resection and postoperative radiotherapy. Patient 3 developed ENB over the left zygomatic process of the maxilla 4 years after a cranioendoscopic resection and postoperative radiation therapy for ENB of the ethmoid sinuses with intracranial extension. The possibility of venous tumor emboli must be considered as a likely etiology. However, alternative explanations include the development of a second primary or potential transformation because of tumor signaling. Conclusion We present 3 cases that may represent metastasis of ENB within the sinonasal tract. © 2015 Wiley Periodicals, Inc. Head Neck 38: E32–E36, 2016