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Relationship between CO 2 laser–induced artifact and glottic cancer surgical margins at variable power doses
Author(s) -
Buchanan Malcolm A.,
Coleman Hedley G.,
Daley James,
Digges James,
Sandler Mark,
Riffat Faruque,
Palme Carsten E.
Publication year - 2016
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24076
Subject(s) - carbon dioxide laser , laser , medicine , artifact (error) , lamina propria , cancer , surgical margin , margin (machine learning) , larynx , laser surgery , pathology , surgery , optics , biology , epithelium , physics , neuroscience , machine learning , computer science
Background The carbon dioxide laser can induce thermal cytologic artifacts at the margin of early glottic squamous cell carcinoma histologic specimens, which makes assessment of the margin difficult. This study assesses and correlates the depth of laser‐induced thermal artifact with laser power rating. Methods The surgical margins of 30 patients with early glottic squamous cell carcinomas who underwent laser resection were reanalyzed retrospectively. Results Thermal damage consisted of collagen denaturation within the vocal cord lamina propria and vocalis muscle, and epithelial structural changes. There was a decrease in depth of tissue artifact with increased power rating ( p > .05). The average depth of thermal damage was 380.83 ± 178.79 μm. Conclusion The laser causes less thermal damage at higher power, presumably because of the increased speed of cutting and reduced contact time with surrounding cells. Knowledge of the depth of thermal artifact is important surgically when ensuring the cancer is excised with sufficient oncologic margin. © 2015 Wiley Periodicals, Inc. Head Neck 38 : E712–E716, 2016