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Neck recurrence of oral squamous cell carcinoma in unusual sites: Retrospective study of 1658 cases
Author(s) -
Feng Zhien,
Niu Li Xuan,
Zhang Jian Yun,
Gao Yan,
Guo Chuan Bin
Publication year - 2016
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.24070
Subject(s) - medicine , basal cell , retrospective cohort study , head and neck , overall survival , surgery , radiology
Background The purpose of this study was to explore the frequency and prognosis of irregular neck recurrences in the prelaryngeal, parotid, and lateral retropharyngeal regions in patients with oral squamous cell carcinoma (OSCC). Methods We conducted a retrospective study. Results Twenty‐four patients (1.4%) had irregular neck recurrences: 17 in the parotid (1.0%), 4 in the prelaryngeal (0.2%), and 3 in the lateral retropharyngeal (0.2%) regions. The 1‐year/5‐year overall survival rates after the N‐relapse date for these areas were 40.0%/25.0%, 42.9%/20.0%, and 33.3%/0%, respectively. Patients with irregular neck recurrences had a poorer salvage success rate than controls (21.7% vs 68.8%, respectively; p < .001) as well as a significantly lower 5‐year disease‐specific survival (23.8% vs 60.8%, respectively; p < .001). Conclusion Patients with OSCC with irregular neck recurrences were extremely rare and had poor prognoses. The management of irregular metastases in patients with OSCC remains challenging for surgeons. Further study will be worthwhile to evaluate the best diagnostic and management strategies for unusual neck recurrences of OSCC. © 2015 Wiley Periodicals, Inc. Head Neck 38 : E680–E686, 2016