Premium
Clinical implications of recent exodontia before diagnosis of gingival squamous cell carcinoma: A new classification
Author(s) -
Cheng ChiSheng,
Chang ChienMing,
Hsiao YingLyung,
Chan ManYee,
Lee ChunYin,
Lee LiTzu,
Wong YongKie
Publication year - 2016
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23896
Subject(s) - medicine , basal cell , analysis of variance , dentistry , head and neck cancer , head and neck squamous cell carcinoma , oncology , cancer
Background The purpose of this study was to clarify the clinical implications of cases with recent dental extractions to establish a new classification of gingival squamous cell carcinoma (SCC). Methods A total of 156 patients were enrolled in this study. The subjects were divided into 3 groups: type I (dentate; n = 46), type II (edentulous; n = 55), and type III (dental extraction; n = 55). Continuous clinical and treatment variables were analyzed by 1‐way analysis of variance (ANOVA) or t test, and categorical variables were evaluated by chi‐square tests. Assessment of 5‐year survival rates were carried out by the Kaplan–Meier analysis, and the influence of related factors was evaluated by the log‐rank test. Result The 55 type III patients showed a high probability of bony invasion (80%) and a lower 5‐year survival rate (48%) than the other 2 groups. Conclusion Our proposed classification may help clinicians to identify patients with gingival SCC who present with more advanced disease status. © 2015 Wiley Periodicals, Inc. Head Neck 38: 339–346, 2016