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Management of multicentric paragangliomas: Review of 24 patients with 60 tumors
Author(s) -
ÁlvarezMorujo Ricardo J. GonzálezOrús,
Ruiz Miguel Ángel Arístegui,
Serafini Daniel Poletti,
Delgado Irene López,
Friedlander Eviatar,
Yurrita Bartolomé Scola
Publication year - 2016
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23894
Subject(s) - paraganglioma , medicine , carotid body , radiology , radiation therapy , modalities , head and neck , surgery , carotid arteries , social science , sociology
Background The purpose of this study was to reflect our experience in the management of multicentric head and neck paragangliomas, including genetic study and counseling, diagnostic tools, types of treatment, and the need for monitoring. Methods A retrospective review of 24 patients with multicentric paraganglioma, including a total of 60 paragangliomas: 37 carotid body tumors, 13 jugulotympanic paragangliomas, and 10 vagal paragangliomas. Results A total of 26 surgical procedures were performed, including the resection of 36 paragangliomas. Four tumors were pending surgery at the time of this review. Radiotherapy was administered in 7 patients with 9 tumors. A “wait‐and‐scan” policy with periodic MRI imaging tests was instituted for 9 patients with 12 paragangliomas. Conclusion The knowledge of the different modalities of management is especially relevant in patients with multicentric paragangliomas. In every case, benefits and potential risks of all treatment options may be taken into consideration for every individual patient. © 2014 Wiley Periodicals, Inc. Head Neck 38: 267–276, 2016