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Prospective study of ultrasound‐guided fine‐needle aspiration cytology and sentinel node biopsy in the staging of clinically negative T1 and T2 oral cancer
Author(s) -
Chaturvedi Pankaj,
Datta Sourav,
Arya Supreeta,
Rangarajan Venkatesh,
Kane Shubhada V.,
Nair Deepa,
Nair Sudhir,
Chaukar Devendra A.,
Pai Prathamesh S.,
Pantvaidya Gouri,
Deshmukh Anuja D.,
Agrawal Archi,
D'Cruz Anil K.
Publication year - 2015
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23787
Subject(s) - medicine , occult , radiology , biopsy , ultrasound , histopathology , metastasis , sentinel node , neck dissection , prospective cohort study , carcinoma , cancer , surgery , breast cancer , pathology , alternative medicine
Background The purpose of this study was to compare sentinel node biopsy (SNB) and ultrasound‐guided fine‐needle aspiration cytology (FNAC) for preoperative evaluation of the N0 neck in T1 to T2 oral cavity squamous cell carcinoma (SCC). Methods Fifty‐one consecutive patients with T1 to T2 N0 oral cavity SCC were included in this study. Preoperative ultrasound was performed in all patients. Ultrasound‐guided FNAC was performed in patients in whom the ultrasound result was reported as indeterminate or positive. SNB was done in all patients followed by elective neck dissection (END). Histopathology of END was considered as the gold standard for all statistical analysis. Results The incidence of occult metastasis was 26.4%. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 71.4%, 100%, 100%, and 90.2% for SNB and 14.3%, 100%, 100%, and 76.5% for ultrasound‐guided FNAC. Conclusion Ultrasound‐guided FNAC lacked sufficient accuracy to detect occult metastases. SNB is a reliable method to detect occult metastasis that has potential to replace END. © 2014 Wiley Periodicals, Inc. Head Neck 37: 1504–1508, 2015