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Unknown primary mucoepidermoid carcinoma: Diagnosis and treatment
Author(s) -
Trosman Samuel,
Chute Deborah,
Wood Benjamin,
Lamarre Eric
Publication year - 2015
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23766
Subject(s) - medicine , mucoepidermoid carcinoma , cervical lymph nodes , primary tumor , biopsy , lymph , lymph node , radiation therapy , carcinoma , radiology , neck mass , positron emission tomography , metastasis , salivary gland , pathology , cancer
Background Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor. The majority of MECs occur in major or intraoral minor salivary glands. Herein, we present a case of MEC metastatic to cervical lymph nodes with an unknown primary site and discuss diagnostic and treatment options. Methods and Results The patient was a 43‐year‐old man who presented with a large right‐sided neck mass. Excisional biopsy demonstrated MEC involving multiple lymph nodes. Subsequent positron emission tomography (PET)/CT and multiple biopsies of potential primary sites failed to localize the primary tumor. The patient was treated with radiation to the ipsilateral neck and parotid/submandibular glands and has no evidence of disease 1 year after completion of treatment. Conclusion MEC presenting as cervical lymph node metastasis with an undiagnosed primary site is extremely rare. We report results of our literature review and provide a rationale for our experience in treating unknown primary MEC. © 2014 Wiley Periodicals, Inc. Head Neck 37 : E22‐E25, 2015