Sigmoid sinus occlusion infiltrated by inflammatory myofibroblastic tumor from mastoid

Background Inflammatory myofibroblastic tumor (IMT) and some types of immunoglobulin (Ig) G4‐related disease are often involved in the spectrum of inflammatory pseudotumor (IPT) and the concept of IgG4‐related IPT/IMT has recently been proposed. Methods A 38‐year‐old man complained of initial symptoms of blurred vision and headache. Results A tumor was found in the right mastoid, which caused occlusion of the right sigmoid sinus and intracranial hypertension. A diagnosis of IMT with IgG4+ plasma cell infiltration was established by surgical, pathological, and immunohistochemistry findings. His symptoms were completely relieved after corticosteroid therapy and no recurrence was detected during 22 months of follow‐up. Conclusion A case with cerebral venous sinus infiltrated by IMTs in the head and neck has never been reported; corticosteroid therapy proved satisfactory in IMT with IgG4+ plasma cell infiltration. © 2014 Wiley Periodicals, Inc. Head Neck 37 : E4–E7, 2015