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Sigmoid sinus occlusion infiltrated by inflammatory myofibroblastic tumor from mastoid
Author(s) -
Wang Jingye,
Sun Zhongwu,
Zhuo Shengxia,
Wang Kai
Publication year - 2015
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23704
Subject(s) - medicine , pathological , occlusion , infiltration (hvac) , plasma cell granuloma , immunohistochemistry , inflammatory pseudotumor , surgery , pathology , radiology , lesion , physics , thermodynamics
Background Inflammatory myofibroblastic tumor (IMT) and some types of immunoglobulin (Ig) G4‐related disease are often involved in the spectrum of inflammatory pseudotumor (IPT) and the concept of IgG4‐related IPT/IMT has recently been proposed. Methods A 38‐year‐old man complained of initial symptoms of blurred vision and headache. Results A tumor was found in the right mastoid, which caused occlusion of the right sigmoid sinus and intracranial hypertension. A diagnosis of IMT with IgG4+ plasma cell infiltration was established by surgical, pathological, and immunohistochemistry findings. His symptoms were completely relieved after corticosteroid therapy and no recurrence was detected during 22 months of follow‐up. Conclusion A case with cerebral venous sinus infiltrated by IMTs in the head and neck has never been reported; corticosteroid therapy proved satisfactory in IMT with IgG4+ plasma cell infiltration. © 2014 Wiley Periodicals, Inc. Head Neck 37 : E4–E7, 2015

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