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Prognostic quality of the Union Internationale Contre le Cancer/American Joint Committee on Cancer TNM classification, 7th edition, for cancer of the maxillary sinus
Author(s) -
Kreppel Matthias,
Amir Manawi NilofarNatalie,
Scheer Martin,
Nickenig HansJoachim,
Rothamel Daniel,
Dreiseidler Timo,
Drebber Uta,
Zinser Max,
Zöller Joachim E.,
Guntinas–Lichius Orlando,
Preuss Simon Florian
Publication year - 2015
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23612
Subject(s) - medicine , cancer , maxillary sinus , cancer staging , surgery
Background Carcinomas of the maxillary sinus are classified according to the Union Internationale Contre le Cancer (UICC)/American Joint Committee on Cancer (AJCC) TNM classification. The purpose of this study was to assess the prognostic significance of the UICC/AJCC TNM classification seventh edition, which was introduced in 2010. Methods One hundred thirteen patients with malignant tumors of the maxillary sinus were included in this study. The prognostic impact of the TNM classification and the UICC/AJCC seventh edition's stage grouping were analyzed in univariate and multivariate analysis. Results The UICC/AJCC stage grouping, the T classification, and the N classification had a significant impact on overall survival (OS) in univariate analysis ( p < .05). No significant differences were observed between the groups T4a and T4b ( p = .109). In multivariate analysis, the UICC/AJCC stage grouping ( p = .031), the N classification ( p = .014), and age ( p < .001) had a significant impact on OS. Conclusion Although UICC/AJCC stage grouping and the N classification provided a significant prediction of OS in univariate and multivariate analysis, T classification only influenced OS in univariate analysis. © 2014 Wiley Periodicals, Inc. Head Neck 37: 400–406, 2015