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Radiotherapy for a repeatedly recurrent ameloblastoma with malignant transformation
Author(s) -
Huang ChunMing,
Chen JinYi,
Chen ChungHo,
Huang ChihJen
Publication year - 2014
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23257
Subject(s) - ameloblastoma , medicine , malignant transformation , radiation therapy , parapharyngeal space , skull , adamantinoma , surgery , radiology , maxilla , pathology , dentistry
Background The role of radiation therapy (RT) for ameloblastoma remains controversial and undetermined due to the rarity of the disease. Methods A case of repeatedly recurrent ameloblastoma with malignant transformation is presented. The clinical course and managements are described. Results The 63‐year‐old man had a recurrent ameloblastoma in the left mandible. Five years after the first surgical resection, he underwent 8 more rounds of surgical excision of the recurrent tumors. The malignant transformation occurred and the unresectable tumor invaded the masticator space, parapharyngeal space, and skull base. He received 3‐dimensional conformal RT, at the dose of 66 Gray (Gy) in 33 fractions. The ulcerative exophytic mass had regressed gradually. After follow‐up of 28 months, the tumor was well controlled. Conclusions RT seems to be a feasible treatment option for recurrent ameloblastoma with malignant transformation. © 2013 Wiley Periodicals, Inc. Head Neck 36 : E1–E3, 2014