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Survival impact of pulmonary metastasectomy for patients with head and neck cancer
Author(s) -
Miyazaki Takuya,
Hasegawa Yasuhisa,
Hanai Nobuhiro,
Ozawa Taijirou,
Hirakawa Hitoshi,
Suzuki Atsushi,
Okamoto Hiroki,
Harata Ikuma
Publication year - 2013
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.23232
Subject(s) - metastasectomy , medicine , head and neck , head and neck cancer , metastasis , lung , overall survival , oncology , surgery , radiology , cancer
Background The purpose of this study was to evaluate the survival impact and prognostic factors of pulmonary metastasectomy in patients with pulmonary metastasis from head and neck cancer. Methods A retrospective study of 69 patients was analyzed. Twenty‐four patients (35%) underwent pulmonary metastasectomy, and the remaining 45 patients (65%) were treated with chemotherapy or best supportive care. Results The 1‐year overall survival (OS) of 69 patients was 28%. Pulmonary metastasectomy ( p = .01) and histology ( p < .001) had a significant impact on the prognosis. One‐year OS of patients who underwent metastasectomy and those who did not was 90% and 35%, respectively. In the metastasectomy group, recurrence of primary ahead of lung metastasis ( p = .006) and disease‐free interval (DFI; ≤21.4 months; p = .046) were significant negative prognostic factors. Conclusion Pulmonary metastasectomy has an impact on survival in carefully selected patients, especially for those with a long DFI and with no recurrence of primary cancer ahead of lung metastasis. © 2013 Wiley Periodicals, Inc. Head Neck 35: 1745–1751, 2012