Premium
CO 2 laser surgery in elderly patients with glottic carcinoma: Univariate and multivariate analyses of results
Author(s) -
Lucioni Marco,
Bertolin Andy,
Rizzotto Giuseppe,
Accordi Daria,
Giacomelli Luciano,
Marioni Gino
Publication year - 2012
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.22907
Subject(s) - medicine , anterior commissure , laser surgery , surgery , cordectomy , multivariate analysis , glottis , transoral laser microsurgery , univariate analysis , carcinoma , larynx , posterior commissure , laryngeal neoplasm , laser , physics , nucleus , psychiatry , optics
Background There are limited data on the role of laser‐assisted surgery for early glottic cancer in elderly patients. Methods This retrospective study was conducted on a series of 130 consecutive cases of early glottic carcinoma occurring in elderly patients (>65 years old) treated with CO 2 laser surgery. Results The overall and disease‐specific survival rates were 87.7% and 99.2%, respectively. The rates of local disease control after primary laser surgery, ultimate local control with laser alone, and laryngeal preservation were 84.6%, 93.8%, and 96.9%, respectively. A shorter disease‐free survival (DFS) was associated with the involvement of 1 or more specific laryngeal regions (arytenoids, ventricle, anterior commissure, vocal muscle, subglottis) ( p = .01) and the status of the surgical margins ( p = .002); on multivariate analysis, only the latter remained prognostically significant vis‐à‐vis the DFS ( p = .002). Conclusions Even in elderly patients with early glottic carcinoma, endoscopic laser surgery is an effective treatment. © 2012 Wiley Periodicals, Inc. Head Neck , 2012