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Lipoleiomyosarcoma of the larynx
Author(s) -
Trijolet J. P.,
Lescanne E.,
Morinière S.,
Robier A.,
Bakhos D.
Publication year - 2013
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.22905
Subject(s) - epiglottis , medicine , larynx , dysphagia , throat , lesion , liposarcoma , head and neck , nose , surgery , resection margin , radiology , resection , pathology , sarcoma
Background Lipoleiomyosarcoma is a rare tumor consisting of well‐differentiated liposarcoma and leiomyosarcoma. The ear–nose–throat location of lipoleiomyosarcoma has not been previously described. Methods and Results A 37‐year‐old man with a dysphagia had a dyspnea after an endoscopy. A large tumor was exteriorized from the man's mouth. The lesion was pedicled to the epiglottis. A histologic examination determined that the tumor was a lipoleiomyosarcoma. MDM2 and CDK4 gene amplification were positive. Due to the risk of recurrence, a second intervention was performed to complete the excision. Conclusion These tumors develop in cavities slowly and gradually. The treatment of this lesion is surgical with a sufficient resection margin. © 2012 Wiley Periodicals, Inc. Head Neck, 2013