Lipoleiomyosarcoma of the larynx | Zendy

Trijolet J. P. | Zendy; Lescanne E. | Zendy; Morinière S. | Zendy; Robier A. | Zendy; Bakhos D. | Zendy

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Lipoleiomyosarcoma of the larynx

Author(s) -

Trijolet J. P.,

Lescanne E.,

Morinière S.,

Robier A.,

Bakhos D.

Publication year - 2013

Publication title -

head and neck

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.012

H-Index - 127

eISSN - 1097-0347

pISSN - 1043-3074

DOI - 10.1002/hed.22905

Subject(s) - epiglottis , medicine , larynx , dysphagia , throat , lesion , liposarcoma , head and neck , nose , surgery , resection margin , radiology , resection , pathology , sarcoma

Background Lipoleiomyosarcoma is a rare tumor consisting of well‐differentiated liposarcoma and leiomyosarcoma. The ear–nose–throat location of lipoleiomyosarcoma has not been previously described. Methods and Results A 37‐year‐old man with a dysphagia had a dyspnea after an endoscopy. A large tumor was exteriorized from the man's mouth. The lesion was pedicled to the epiglottis. A histologic examination determined that the tumor was a lipoleiomyosarcoma. MDM2 and CDK4 gene amplification were positive. Due to the risk of recurrence, a second intervention was performed to complete the excision. Conclusion These tumors develop in cavities slowly and gradually. The treatment of this lesion is surgical with a sufficient resection margin. © 2012 Wiley Periodicals, Inc. Head Neck, 2013

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