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High‐grade primary leiomyosarcoma in the mandible: Diagnosis and treatment
Author(s) -
Rege Inara Carneiro Costa,
Costa Nádia Lago,
Batista Aline Carvalho,
da Silva Clóvis Martins,
Meneghini Alexandre João,
Mendonça Elismauro Francisco
Publication year - 2013
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21853
Subject(s) - medicine , leiomyosarcoma , mandible (arthropod mouthpart) , lesion , biopsy , radiology , surgery , botany , biology , genus
Background Leiomyosarcoma is a malignant tumor that originates in smooth muscle cells and is rarely found in the oral cavity. We present a case of high‐grade primary leiomyosarcoma in the mandible and discuss the diagnosis process. Methods The patient was a 64‐year‐old white man who had a slight increase in volume in the left‐side mandible with a radiolucent osteolytic image with the destruction of the mandibular cortex. Incisional biopsy and preoperative examination were performed, including cone beam CT and examination by immunohistochemistry that defined the histologic diagnosis of leiomyosarcoma. The patient underwent reconstruction with an osteocutaneous flap with microvascular anastomosis. Results Two years after the surgery, there was no sign of recurrence of the lesion. Conclusion The use of cone beam CT to define the limits of the lesion and the immunohistochemical findings were essential to establish the treatment plan. © 2011 Wiley Periodicals, Inc. Head Neck, 2013