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Factors associated with recurrence and therapeutic strategies for sinonasal rosai–dorfman disease
Author(s) -
Chen Hai–Hong,
Zhou Shui–Hong,
Wang Shen–Qing,
Teng Xiao–Dong,
Fan Jun
Publication year - 2012
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21832
Subject(s) - rosai–dorfman disease , medicine , disease , paranasal sinuses , nasal cavity , head and neck , sinus (botany) , surgery , dermatology , botany , biology , genus
Background The purpose of this study was to explore the factors associated with the recurrence of Rosai–Dorfman disease (RDD) in the nasal cavity and paranasal sinus. Methods In this study, we conducted a review of the English‐language literature published between 1969 and 2010 on the recurrence of and treatment strategies for sinonasal RDD. Results To our knowledge, 126 cases of RDD have been reported to date. Of the 126 patients, 32 (25.4%) had no recurrence or were alive with no evidence of disease; remission occurred in only 1 patient (0.7%); 69 patients (54.8%) had a recurrent, persistent, or progressive course; and 6 patients (4.8%) died from the disease. In patients with recurrent, persistent, and progressive disease, there was no significant tendency for lymph node involvement. Conclusion Sinonasal RDD is generally described as benign. However, recurrence and fatal outcome have been reported. Our results suggest that the initial modality may affect the recurrence of RDD. © 2011 Wiley Periodicals, Inc. Head Neck , 2011