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Sentinel lymph node biopsy using real‐time fluorescence navigation with indocyanine green in cutaneous head and neck/lip mucosa melanomas
Author(s) -
Hayashi Toshihiko,
Furukawa Hiroshi,
Oyama Akihiko,
Funayama Emi,
Saito Akira,
Yamao Takeshi,
Yamamoto Yuhei
Publication year - 2012
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21651
Subject(s) - indocyanine green , sentinel lymph node , biopsy , medicine , head and neck , fluorescence , sentinel node , pathology , surgery , optics , cancer , physics , breast cancer
Background The triple technique (lymphoscintigraphy, patent‐blue staining, and a gamma probe) constitutes a reliable method for the sentinel lymph node (SLN) biopsy. However, in head and neck melanomas, a shine‐through phenomenon, which occurs because these SLNs are close to the primary focus, is irreversibly problematic. To get around the shine‐through phenomenon, this study uses the fluorescence navigation with indocyanine green (ICG) as well as the triple technique. Methods ICG is a green dye and can be used as a marker with infrared fluorescence. ICG solution is intradermally injected around the tumor. By using Photodynamic Eye (PDE) intraoperatively, it is possible to observe the injected ICG as SLNs in the fluorescence images. Results By use of the fluorescence imaging with ICG, clear identification of the SLN of the case became possible. Conclusions We think the fluorescence navigation with ICG will be a useful option for the SLN biopsy in head and neck melanomas. © 2011 Wiley Periodicals, Inc. Head Neck, 2012