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Contemporary management of sinonasal cancer
Author(s) -
Robbins K. Thomas,
Ferlito Alfio,
Silver Carl E.,
Takes Robert P.,
Strojan Primoẑ,
Snyderman Carl H.,
de Bree Remco,
Haigentz Missak,
Langendijk Johannes A.,
Rinaldo Alessandra,
Shaha Ashok R.,
Hanna Ehab Y.,
Werner Jochen A.,
Suárez Carlos
Publication year - 2011
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21515
Subject(s) - medicine , head and neck cancer , radiation therapy , modalities , disease , head and neck , surgery , therapeutic modalities , cancer , skull , general surgery , intensive care medicine , pathology , physical therapy , sociology , social science
Background. Sinonasal cancer is a relatively uncommon entity encountered by head and neck oncologists, rhinologists, and skull base surgeons. Recent innovations in surgical and nonsurgical therapeutic modalities raise the question of whether there has been any measurable improvement for treatment outcomes. Methods. A retrospective review of data from recent studies that focus on surgery, radiation, and chemotherapy, or combinations thereof, was conducted. Results. Surgery continues to be the preferred treatment and provides the best results, albeit with an inherent bias based on patient selection. For advanced disease (T4 lesions), the survival rate remains only modest. Complications of treatment, including both surgical and radiation therapy, have been reduced. Conclusions. There is a need to improve the efficacy of treatment for this disease. Recommendations for the future direction of therapeutic investigations are outlined. © 2010 Wiley Periodicals, Inc. Head Neck, 2010