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Combined therapy for thyroid squamous cell carcinoma
Author(s) -
De Vos Filip Yves F. L.,
Sewnaik Aniel,
de Wilt J. Hans W.,
Smid Ernst J.,
den Bakker Michael A.,
van Meerten Esther
Publication year - 2012
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21484
Subject(s) - medicine , basal cell , thyroid , paclitaxel , induction chemotherapy , cisplatin , chemotherapy , oncology , head and neck , thyroid carcinoma , head and neck squamous cell carcinoma , surgery , radiology , radiation therapy , head and neck cancer
Background. Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis. Methods and Results. We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy. Conclusions. Our patient now has a recurrence‐free survival of >20 months, longer than the mean survival described in the literature. © 2010 Wiley Periodicals, Inc. Head Neck, 2012