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Localization and identification of parapharyngeal metastases from differentiated thyroid carcinoma by 131 I‐SPECT/CT
Author(s) -
Qiu ZhongLing,
Xu YanHong,
Song HongJun,
Luo QuanYong
Publication year - 2011
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21416
Subject(s) - medicine , parapharyngeal space , metastasis , radiology , thyroid carcinoma , nuclear medicine , carcinoma , spect imaging , thyroid , pathology , cancer
Background Parapharyngeal metastasis is a rare event in differentiated thyroid carcinoma (DTC). The 131 I‐single photon emission CT (SPECT)/CT allows better localization and definition for metastases in DTC. The aim of this study was to assess the value of 131 I‐SPECT/CT for the diagnosis of parapharyngeal metastasis in patients with DTC. Methods Consecutive patients with DTC ( n = 561) treated with 131 I for the ablation of remnant or treatment of metastases were enrolled. A 131 I‐SPECT/CT was performed when there were abnormal findings indicative of parapharyngeal metastasis on 131 I‐whole‐body scan (WBS). Results A total of 15 lesions were found to be parapharyngeal metastasis in 14 of 561 patients with DTC after the use of 131 I‐SPECT/CT. The incidence rate of parapharyngeal metastasis was about 2.5% in DTC. Of the 15 lesions, only 5 lesions were CT‐positive. The remaining 10 lesions were either ignored or indeterminate by the CT alone. Conclusion The 131 I‐SPECT/CT can identify parapharyngeal metastasis at an early stage. Parapharyngeal metastasis in DTC is relatively frequent after the use of 131 I‐SPECT/CT. © 2010 Wiley Periodicals, Inc. Head Neck, 2011