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Enlarged tracheoesophageal puncture after total laryngectomy: A systematic review and meta‐analysis
Author(s) -
Hutcheson Katherine A.,
Lewin Jan S.,
Sturgis Erich M.,
Kapadia Asha,
Risser Jan
Publication year - 2011
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21399
Subject(s) - laryngectomy , medicine , meta analysis , surgery , larynx
Background Enlargement of the tracheoesophageal puncture (TEP) is a challenging complication after laryngectomy with TEP. We sought to estimate the rate of enlarged puncture, associated pneumonia rates, potential risk factors, and conservative treatments excluding complete surgical TEP closure. Methods A systematic review was conducted (1978–2008). A summary risk estimate was calculated using a random‐effects meta‐analysis model. Results Twenty‐seven peer‐reviewed manuscripts were included. The rate of enlarged puncture and/or leakage around the prosthesis was reported in 23 articles (range, 1% to 29%; summary risk estimate, 7.2%; 95% confidence interval [CI], 4.8% to 9.6%). Temporary removal of the prosthesis and TEP‐site injections were the most commonly reported conservative treatments. Prosthetic diameter ( p = .076) and timing of TEP ( p = .297) were analyzed as risk factors; however, radiotherapy variables were inconsistently reported. Conclusion The overall risk of enlarged puncture seems relatively low, but it remains a rehabilitative challenge. Future research should clearly establish risk factors for enlarged puncture and optimal conservative management. © 2010 Wiley Periodicals, Inc. Head Neck, 2011