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Importance of intraoperative parathyroid hormone measurement in the diagnosis of parathyroid lipoadenoma
Author(s) -
Lee Ann Y.,
Wang Beverly Y.,
Heller Keith S.
Publication year - 2011
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21339
Subject(s) - parathyroid hormone , medicine , calcium
Background. Parathyroid lipoadenoma is an uncommon tumor that may be difficult to diagnose on intraoperative frozen section. Intraoperative parathyroid hormone (PTH) measurement is useful in assessing the adequacy of parathyroidectomy. This case demonstrates the value of intraoperative PTH measurement in recognizing a parathyroid lipoadenoma.Methods and Results. A case of a 62‐year‐old woman with primary hyperparathyroidism in which intraoperative PTH measurement helped confirm the diagnosis of parathyroid lipoadenoma is presented.Conclusions. In patients with primary hyperparathyroidism, a significant decrease in intraoperative PTH confirms that an enlarged parathyroid with normal to low cellularity containing abundant fat is a lipoadenoma and that further exploration is not necessary. © 2010 Wiley Periodicals, Inc. Head Neck, 2011