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Detection of metachronous esophageal squamous carcinoma in patients with head and neck cancer with use of transnasal esophagoscopy
Author(s) -
Su YanYe,
Fang FuMin,
Chuang HuiChing,
Luo ShengDean,
Chien ChihYen
Publication year - 2010
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21252
Subject(s) - medicine , squamous carcinoma , hypopharyngeal cancer , carcinoma , esophageal cancer , head and neck cancer , head and neck squamous cell carcinoma , cancer , stage (stratigraphy) , basal cell , oncology , paleontology , biology
Background The use of transnasal esophagoscopy was examined for detecting metachronous esophageal squamous carcinoma in patients with head and neck squamous cell carcinoma (HNSCC). Methods In all, 398 transnasal esophagoscopies were performed in 293 previously treated patients with HNSCC between December 2007 and January 2009. Results Metachronous esophageal squamous carcinoma was detected in 15 (5.1%) patients. The prevalence rate was 15.9% (7/44) in patients with hypopharyngeal cancer, significantly higher than the 8.3% (2/24) with laryngeal, 7.1% (3/42) with oropharyngeal, and 1.6% (3/183) with oral cancer ( p = .001). The stage distributions of esophageal squamous carcinoma were I–II in 12 (80%) and III–IV in 3 (20%) patients. Subsequently, curative strategies were performed in 13 (87%) patients. Conclusions Transnasal esophagoscopy can be used as a routine survey technique in patients with HNSCC to detect metachronous esophageal squamous carcinoma, especially in those with hypopharyngeal cancer. © 2009 Wiley Periodicals, Inc. Head Neck, 2010