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Percutaneous sclerotherapy of massive venous malformations of the face and neck using fibrin glue combined with OK‐432 and pingyangmycin
Author(s) -
Chen Weiliang,
Huang Zhiquan,
Zhang Daming,
Chai Qiang
Publication year - 2010
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21206
Subject(s) - pingyangmycin , sclerotherapy , medicine , percutaneous , fibrin glue , surgery , venous malformation , fibrin , radiology , hemangioma , immunology
Background. Surgical excision is useful only for localized and limited lesions. The purpose of this study was to evaluate the clinical curative effect of percutaneous sclerotherapy of massive venous malformations of the face and neck using fibrin glue combined with OK‐432 and pingyangmycin. Methods. Eighteen patients with massive venous malformations were treated with an injection of fibrin glue combined with OK‐432 and pingyangmycin. Results. All the patients had extreme swelling postoperatively with no major complications. The follow‐up period ranged from 6 to 12 months. Twelve lesions were completely involuted, 4 lesions were mostly involuted, and 2 lesions were partially involuted. All of the patients had normal liver and kidney functions. None of the patients presented with hematologic toxic effects or signs of pulmonary involvement. Conclusion. Percutaneous sclerotherapy using fibrin glue combined with OK‐432 and pingyangmycin provided a simple, safe, and reliable alternative treatment for massive venous malformations. © 2009 Wiley Periodicals, Inc. Head Neck, 2010