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Squamous cell carcinoma of the nasal vestibule 1993–2002: A nationwide retrospective study from DAHANCA
Author(s) -
Agger Andreas,
von Buchwald Christian,
Madsen Anders Rørbæk,
Yde Jesper,
Lesnikova Iana,
Christensen Charlotte Birk,
Foghsgaard Søren,
Christensen Thomas Broe,
Hansen Hanne Sand,
Larsen Susanne,
Bentzen Jens,
Andersen Elo,
Andersen Lisbeth,
Grau Cai
Publication year - 2009
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.21132
Subject(s) - nasal vestibule , medicine , vestibule , head and neck cancer , retrospective cohort study , basal cell , radiation therapy , cancer , otorhinolaryngology , head and neck , surgery , oncology , nasal cavity , radiology , vestibular system
Background. A retrospective nationwide study of cancer of the nasal vestibule was conducted to evaluate classification systems and prognostic factors for treatment outcome.Methods. Patients treated between 1993 and 2002 at head and neck oncology centers in Denmark were included.Results. The 5‐year results were locoregional control 67%, overall survival 50%, cancer‐specific survival 74%. Cancer‐specific survival according to Wang classification was 83%, 63%, and 39% for T1, T2, T3, respectively ( p < .000). Regarding T1 tumors, 5‐year locoregional control for surgery, surgery + radiotherapy (RT), or RT was 94%, 87%, or 61%, respectively ( p < .000). Fifty‐four Gray in 18 fractions was found comparable with 66 Gy in 33 fractions regarding T1 tumors.Conclusion. This national survey is the largest series of nasal vestibule cancer ever published. Wang classification is more prognostic and easier to use than the Union Internationale Contre le Cancer 2002. Surgery or hypofractionated RT can be used for T1 lesions, whereas larger lesions should be treated with combined approach. © 2009 Wiley Periodicals, Inc. Head Neck, 2009