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Evolution of maxillofacial brown tumors after parathyroidectomy in primary hyperparathyroidism
Author(s) -
ReséndizColosia Jaime Alonso,
RodríguezCuevas Sergio Arturo,
FloresDíaz Rutilio,
Juan Martín HernándezSan,
GallegosHernández José Francisco,
BarrosoBravo Sinhué,
GómezAcosta Fernando
Publication year - 2008
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.20905
Subject(s) - medicine , brown tumor , parathyroidectomy , primary hyperparathyroidism , osteitis fibrosa cystica , lesion , osteitis , hyperparathyroidism , maxilla , surgery , mandible (arthropod mouthpart) , anatomy , secondary hyperparathyroidism , calcium , parathyroid hormone , biology , osteomyelitis , botany , genus
Abstract Background. Brown tumor occasionally affects the facial bones. Clinically, these lesions can be mistaken for a neoplasm. Opinions are divided on the course of management of the bony lesions once parathyroidectomy has been carried out. Methods. We treated 22 patients with primary hyperparathyroidism and osteitis fibrosa cystica and observed their clinical and biochemical recovery. Results. Fifteen patients (68.2%) had brown tumors in mandible, and 7 (31.8%) in maxilla. After parathyroidectomy, 21 patients had normal total serum calcium values. All brown tumors presented a spontaneous progressive regression; in 18cases, regression was total, with a mean time period of 10months. Two patients had partial regression after nearly 2years. Another 2 patients were lost to follow‐up. Conclusions. After successful parathyroid surgery, the bony lesions tended to regress spontaneously, either partially or completely. However, if the lesion is disfiguring or symptomatic, surgical excision may be indicated. © 2008 Wiley Periodicals, Inc. Head Neck, 2008