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Clinical outcome of T1 glottic carcinoma since the introduction of endoscopic CO 2 laser surgery as treatment option
Author(s) -
Sjögren Elisabeth V.,
Langeveld Ton P. M.,
Baatenburg de Jong Robert J.
Publication year - 2008
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.20852
Subject(s) - medicine , laser surgery , surgery , larynx , radiation therapy , carcinoma , laser , physics , optics
Background Since the introduction of endoscopic laser surgery at our institution in 1996, 189 patients have been treated for T1 glottic carcinoma. Methods Treatment allocation (radiotherapy vs laser surgery) and outcome were evaluated. Results Fifty‐one percent of T1a lesions were considered suitable for laser surgery. Sixteen percent of T1a patients treated with laser surgery needed additional treatment because of positive resection margins. Overall local control and larynx preservation were 89% and 96%. Both were poorer in T1a patients with larger lesions treated with radiotherapy (local control 75% versus 89%, p = .05, larynx preservation 83% vs 100%, p = .001). Conclusion Outcome for T1a patients selected for laser surgery is excellent. In patients with larger lesions treated with radiotherapy, outcome is inferior to patients selected for laser surgery, but also to that reported for (unselected) T1a carcinomas treated with radiotherapy in literature. Strategies to improve treatment results in patients deemed unsuitable for laser surgery should be designed. © 2008 Wiley Periodicals, Inc. Head Neck, 2008