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Primary laryngeal natural killer/T‐cell lymphoma—Report of a rare case
Author(s) -
Monobe Hiroko,
Nakashima Masato,
Tominaga Kunihiko
Publication year - 2008
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.20803
Subject(s) - larynx , lymphoma , medicine , lesion , head and neck , pathology , disease , rare disease , chemotherapy , surgery
Background Natural killer (NK)/T‐cell lymphoma involving the larynx is a rare entity, and its clinical picture has not been described. Methods and Results A 73‐year‐old man had a granulomatous tumor involving the larynx. Multiple biopsies over 1 year were needed to reach an accurate diagnosis of NK/T‐cell lymphoma. This patient died of the disease despite the use of chemotherapy. Conclusion To the best of our knowledge, this is the second case of primary laryngeal NK/T‐cell that illustrates its clinical picture. In the early stage of the disease, this type of tumor can present as granulous tumor‐like lesion without a definite destructive lesion. This tumor type should be kept in mind in tumors that are difficult to diagnose, especially in Asian populations. © 2008 Wiley Periodicals, Inc. Head Neck, 2008