Premium
Influence of heat and moisture exchanger respiratory load on transcutaneous oxygenation in laryngectomized individuals: A randomized crossover study
Author(s) -
Zuur J. Karel,
Muller Sara H.,
Sinaasappel Michiel,
Hart Guus A. M.,
van Zandwijk Nico,
Hilgers Frans J. M.
Publication year - 2007
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.20643
Subject(s) - medicine , crossover study , anesthesia , randomized controlled trial , ventilation (architecture) , mechanical ventilation , mechanical engineering , alternative medicine , pathology , engineering , placebo
Background High‐resistance heat and moisture exchangers (HMEs) have been reported to increase transcutaneous oxygenation (tcpO 2 ) values in laryngectomized individuals and to negatively influence patient compliance. The goal of the present study was to validate earlier published results on short‐term transcutaneous oxygenation changes by high‐resistance HMEs. Methods We conducted a randomized crossover study, monitoring the influence of an HME on tcpO 2 over a 2‐hour time interval in 20 subjects. Results No evidence of an immediate HME effect (95% CI: −14.9–13.3 mm Hg, p = .91), or a time‐dependent HME effect (95% CI: −.121 – .172 mm Hg/minute, p = .74), on tcpO 2 was found. After fitting the statistical model without time dependency, again no evidence of HME presence was seen (95% CI: −.5 mm Hg – 3.6 mm Hg, p = .15). Conclusion In contrast to earlier suggestions, there is no evidence of increased tcpO 2 levels by high‐resistance HMEs in laryngectomized individuals. Thus, using such HMEs has no added clinical value in this respect. © 2007 Wiley Periodicals, Inc. Head Neck, 2007