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Second malignant neoplasia in early (TIS‐T1) glottic carcinoma
Author(s) -
Sjögren Elisabeth V.,
Snijder Simone,
van Beekum Joost,
Baatenburg de Jong Robert Jan
Publication year - 2006
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.20453
Subject(s) - medicine , incidence (geometry) , carcinoma , cancer registry , population , head and neck cancer , radiology , cancer , oncology , gastroenterology , physics , environmental health , optics
Background. We performed a population‐based study to determine the incidence and patterns of second malignant neoplasia (SMN) in early glottic carcinoma. Methods. All patients diagnosed with Tis‐T1 glottic carcinoma in the southwest of the Netherlands between 1982 and 1993 (359) were included. Sources of the data were patient charts and the regional cancer registry. Results. SMN incidence was 27.7% (median follow‐up, 89 months). Observed‐to‐expected ratios were increased for lung, bladder, urinary tract, pancreatic, colorectal, and head and neck cancers. The incidence of head and neck and esophageal cancer was surprisingly low. Conclusions. Patients with early glottic carcinoma are at a reliably increased risk of the development of tumors not only in the areas of the upper aerodigestive tract, but also in the bladder, pancreas, and colorectum. The low incidence of head and neck and esophageal tumors does not appear to support routine panendoscopy in this patient population. © 2006 Wiley Periodicals, Inc. Head Neck 28:501–507, 2006