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Osteoblastoma of the mandible: Clinicopathologic study of four cases and literature review
Author(s) -
Capodiferro Saverio,
Maiorano Eugenio,
Giardina Carmela,
Lacaita Maria Grazia,
Lo Muzio Lorenzo,
Favia Gianfranco
Publication year - 2005
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/hed.20192
Subject(s) - osteoblastoma , medicine , mandible (arthropod mouthpart) , osteoid , radiography , maxilla , osteoid osteoma , pathology , radiology , anatomy , osteosarcoma , botany , biology , genus
Background. Osteoblastoma is a benign bone tumor accounting for 1% of all bone tumors; it commonly involves the spine and the sacrum of young individuals, with less than 5% being localized to the posterior mandible. In view of its rarity in the maxilla and mandible, osteoblastoma is rarely diagnosed as such in the absence of interdisciplinary cooperation. Methods. A retrospective study of four benign osteoblastomas was performed based on a review of the clinical, radiographic, and histopathologic features of all cases. Results. The tumors involved the posterior mandible of young patients (age range, 10–21 years; two male and two female patients) and appeared as painful bone expansions. Radiologically, they were poorly defined, radiolucent/radiopaque lesions containing calcifications and not showing sclerotic borders or periosteal reactions. Histologically, they were composed of osteoid and woven bone surrounded by plump osteoblast‐like cells with interposed fibroblasts, inflammatory cells, and red blood cells. All patients were disease free after prolonged follow‐up. Conclusions. Osteoblastomas may be distinguished from other bone tumors, fibro‐osseous lesions, and odontogenic neoplasms on the basis of integrated clinical, radiologic, and histologic features and usually manifest an indolent clinical course. © 2005 Wiley Periodicals, Inc. Head Neck 27: XXX–XXX, 2005