Premium
Valuing health‐related quality of life: An EQ ‐5 D ‐5 L value set for E ngland
Author(s) -
Devlin Nancy J.,
Shah Koonal K.,
Feng Yan,
Mulhern Brendan,
Hout Ben
Publication year - 2018
Publication title -
health economics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 109
eISSN - 1099-1050
pISSN - 1057-9230
DOI - 10.1002/hec.3564
Subject(s) - eq 5d , valuation (finance) , quality adjusted life year , psychological intervention , time trade off , quality of life (healthcare) , face value , minimum data set , set (abstract data type) , quality (philosophy) , value (mathematics) , anxiety , psychology , actuarial science , medicine , econometrics , statistics , health related quality of life , computer science , mathematics , economics , cost effectiveness , psychiatry , nursing , philosophy , epistemology , programming language , disease , finance , pathology , nursing homes
A new version of the EQ‐5D, the EQ‐5D‐5L, is available. The aim of this study is to produce a value set to support use of EQ‐5D‐5L data in decision‐making. The study design followed an international research protocol. Randomly selected members of the English general public completed 10 time trade‐off and 7 discrete choice experiment tasks in face‐to‐face interviews. A 20‐parameter hybrid model was used to combine time trade‐off and discrete choice experiment data to generate values for the 3,125 EQ‐5D‐5L health states. Valuation data are available for 996 respondents. Face validity of the data has been demonstrated, with more severe health states generally given lower values. Problems with pain/discomfort and anxiety/depression received the greatest weight. Compared to the existing EQ‐5D‐3L value set, there are considerably fewer “worse than dead” states (5.1%, compared with over one third), and the minimum value is higher. Values range from −0.285 (extreme problems on all dimensions) to 0.950 (for health states 11211 and 21111). Results have important implications for users of the EQ‐5D‐5L both in England and internationally. Quality‐adjusted life year gains from interventions seeking to improve very poor health may be smaller using this value set and may previously have been overestimated.