Open AccessMicrowave‐assisted synthesis of 2‐amino and 2‐azetidinonyl 5‐(2‐benzoyl‐phenoxymethyl) 1,3,4‐oxadiazoles
Author(s) -
Khanum Shaukath Ara,
Shashikanth S.,
Sudha B. S.
Publication year - 2004
Publication title -
heteroatom chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.283
H-Index - 42
eISSN - 1098-1071
pISSN - 1042-7163
DOI - 10.1002/hc.10210
Subject(s) - chemistry , heteroatom , benzophenone , microwave irradiation , oxadiazole , microwave , microwave heating , combinatorial chemistry , organic chemistry , ring (chemistry) , catalysis , physics , quantum mechanics
A simple high yielding method for the integration of heterocyclic rings viz. 1,3,4‐oxadiazole and azetidin‐2‐one at the benzophenone nucleus has been developed starting from substituted 2‐hydroxybenzophenones, and by using mild conditions, wet solid surface, and microwave irradiation. A comparison of this microwave‐accelerated reaction with conventional heating condition is also illustrated. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:37–42, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10210