Open AccessA new technique for pet slice orientation and MRI‐PET coregistration
Author(s) -
Grabowski T. J.,
Damasio H.,
Frank R.,
Hichwa R. D.,
Boles Ponto L. L.,
Watkins G. L.
Publication year - 1994
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.460020302
Subject(s) - fiducial marker , positron emission tomography , orientation (vector space) , computer science , magnetic resonance imaging , pet imaging , computer vision , artificial intelligence , nuclear medicine , medicine , radiology , mathematics , geometry
We report and validate a technique for magnetic resonace imaging (MRI) positron emission tomography (PET) coregistration and the optimization of PET slice orientation that enhances and complements existing techniques. The technique depends on an external fiducial system and on software that models the relationship of the PET gantry with respect to a three‐dimensional (3D) MR reconstruction of each subject's brain anatomy. The technique offers the possibility of using individual neuroanatomical information to plan PET activation studies. Estimated 3D errors average 3 mm in [ 15 O]H 2 O PET activation studies. In‐plane interinjection movement averages less than 1 mm. The resulting MRI‐PET coregistration provides a basis for bringing neuroanatomical information to bear on a number of issues critical for the interpretation of functional imaging studies. © 1995 Wiley‐Liss, Inc.