Open AccessFunctional neuroanatomy of verbal free recall: A replication study
Author(s) -
Becker James T.,
Mintun Mark A.,
Diehl David J.,
Dobkin Jeffrey,
Martidis Adam,
Madoff David C.,
Dekosky Steven T.
Publication year - 1994
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.460010406
Subject(s) - psychology , recall , temporal lobe , neuroanatomy , free recall , verbal memory , neuroscience , prefrontal cortex , cognitive psychology , audiology , cognition , medicine , epilepsy
The functional neuroanatomy of verbal memory was investigated using verbal free recall during H 2 15 O positron emission tomography (PET). Twelve young (25–40 years old) normal control subjects participated in eight scans during a single scanning session during which they performed three memory tasks differing by word list length. Four subjects also had scans during a “rest” condition. Temporal lobe activation was observed during all tasks, including single‐word repetition. The frontal cortices, specifically Brodmann areas 9 and 10, were activated only when the recall word lists exceeded the memory spans (i. e., 12 and 15 words). Activation was also observed in the anterior cingulate cortex (BA24 and BA32). These data, obtained using a within‐subject design, extend previously reported findings that used mixed within‐and between‐subject designs and demonstrate important functional components of normal auditoryverbal short‐term memory. © 1994 Wiley‐Liss, Inc.