Open AccessAnalysis of functional MRI time‐series
Author(s) -
Friston K. J.,
Jezzard P.,
Turner R.
Publication year - 1994
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.460010207
Subject(s) - functional magnetic resonance imaging , sensory system , hemodynamics , statistical parametric mapping , haemodynamic response , parametric statistics , function (biology) , measure (data warehouse) , magnetic resonance imaging , mathematics , computer science , neuroscience , pattern recognition (psychology) , artificial intelligence , psychology , statistics , data mining , biology , medicine , cardiology , radiology , heart rate , evolutionary biology , blood pressure
Abstract A method for detecting significant and regionally specific correlations between sensory input and the brain's physiological response, as measured with functional magnetic resonance imaging (MRI), is presented in this paper. The method involves testing for correlations between sensory input and the hemodynamic response after convolving the sensory input with an estimate of the hemodynamic response function. This estimate is obtained without reference to any assumed input. To lend the approach statistical validity, it is brought into the framework of statistical parametric mapping by using a measure of cross‐correlations between sensory input and hemodynamic response that is valid in the presence of intrinsic autocorrelations. These autocorrelations are necessarily present, due to the hemodynamic response function or temporal point spread function. © 1994 Wiley‐Liss, Inc.