Open AccessCover Image
Author(s) -
Ishaque Mariam,
Manning Janessa H.,
Woolsey Mary D.,
Franklin Crystal G.,
Tullis Elizabeth W.,
Beckmann Christian F.,
Fox Peter T.
Publication year - 2017
Publication title -
human brain mapping
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.23771
Subject(s) - psychology , functional connectivity , resting state fmri , cover (algebra) , neuroscience , mechanical engineering , engineering
COVER ILLUSTRATION: Locked‐in Children. Children resuscitated after near‐fatal drowning often incur anoxic brain injury (ABI). Locked‐in syndrome — a condition defined by the co‐occurrence of quadriplegia and aphonia — is a previously unreported consequence of pediatric ABI. In this issue, Ishaque and colleagues report ICA analysis of resting‐state fMRI (rs‐fMRI) and network‐based quantitative behavioral assessments in 10 children with drowning‐induced ABI, each of whom exhibit some form of lockedin syndrome. On a per‐subject basis, rs‐fMRI network preservation closely paralleled behavioral results (r = 0.74), suggesting that rs‐fMRI has the potential to assess cognitive status when communication is compromised.