Open AccessStructural abnormalities in the dyslexic brain: A meta‐analysis of voxel‐based morphometry studies
Author(s) -
Richlan Fabio,
Kronbichler Martin,
Wimmer Heinz
Publication year - 2013
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.22127
Subject(s) - voxel based morphometry , dyslexia , voxel , sulcus , psychology , hum , brain morphometry , temporal lobe , neuroscience , superior temporal sulcus , brain anatomy , grey matter , white matter , reading (process) , magnetic resonance imaging , medicine , functional magnetic resonance imaging , art , performance art , political science , law , epilepsy , radiology , art history
We used coordinate‐based meta‐analysis in order to objectively quantify gray matter abnormalities reported in nine Voxel‐Based Morphometry studies of developmental dyslexia. Consistently across studies, reduced gray matter volume in dyslexic readers was found in the right superior temporal gyrus and left superior temporal sulcus. These results were related to findings from previous meta‐analyses on functional brain abnormalities in dyslexic readers. Convergence of gray matter reduction and reading‐related underactivation was found for the left superior temporal sulcus. Recent studies point to the presence of both functional and structural abnormalities in left temporal and occipito‐temporal brain regions before reading onset. Hum Brain Mapp 34:3055–3065, 2013. © 2012 Wiley Periodicals, Inc.