Open AccessCortical gamma‐oscillations modulated by auditory–motor tasks‐intracranial recording in patients with epilepsy
Author(s) -
Nagasawa Tetsuro,
Rothermel Robert,
Juhász Csaba,
Fukuda Miho,
Nishida Masaaki,
Akiyama Tomoyuki,
Sood Sandeep,
Asano Eishi
Publication year - 2010
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.20963
Subject(s) - superior temporal gyrus , postcentral gyrus , precentral gyrus , psychology , neuroscience , laterality , middle temporal gyrus , motor cortex , audiology , cued speech , epilepsy , somatosensory system , medicine , functional magnetic resonance imaging , magnetic resonance imaging , cognitive psychology , stimulation , radiology
Human activities often involve hand‐motor responses following external auditory–verbal commands. It has been believed that hand movements are predominantly driven by the contralateral primary sensorimotor cortex, whereas auditory–verbal information is processed in both superior temporal gyri. It remains unknown whether cortical activation in the superior temporal gyrus during an auditory–motor task is affected by laterality of hand‐motor responses. Here, event‐related γ‐oscillations were intracranially recorded as quantitative measures of cortical activation; we determined how cortical structures were activated by auditory‐cued movement using each hand in 15 patients with focal epilepsy. Auditory–verbal stimuli elicited augmentation of γ‐oscillations in a posterior portion of the superior temporal gyrus, whereas hand‐motor responses elicited γ‐augmentation in the pre‐ and postcentral gyri. The magnitudes of such γ‐augmentation in the superior temporal, precentral, and postcentral gyri were significantly larger when the hand contralateral to the recorded hemisphere was required to be used for motor responses, compared with when the ipsilateral hand was. The superior temporal gyrus in each hemisphere might play a greater pivotal role when the contralateral hand needs to be used for motor responses, compared with when the ipsilateral hand does. Hum Brain Mapp, 2010. © 2010 Wiley‐Liss, Inc.