Open AccessSex specificity of ventral anterior cingulate cortex suppression during a cognitive task
Author(s) -
Butler Tracy,
ImperatoMcGinley Julianne,
Pan Hong,
Voyer Daniel,
CunninghamBussel Amy Christine,
Chang Luke,
Zhu YuanShan,
Cordero Juan J.,
Stern Emily,
Silbersweig David
Publication year - 2007
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.20340
Subject(s) - anterior cingulate cortex , cognition , psychology , mental rotation , cingulate cortex , neuroscience , association (psychology) , cognitive psychology , central nervous system , psychotherapist
Ventral anterior cingulate cortex (vACC) is a highly interconnected brain region considered to reflect the sometimes competing demands of cognition and emotion. A reciprocal relationship between vACC and dorsal ACC (dACC) may play a role in maintaining this balance between cognitive and emotional processing. Using functional MRI in association with a cognitively‐demanding visuospatial task (mental rotation), we found that only women demonstrated vACC suppression and inverse functional connectivity with dACC. Sex differences in vACC functioning—previously described under conditions of negative emotion—are extended here to cognition. Consideration of participant sex is essential to understanding the role of vACC in cognitive and emotional processing. Hum Brain Mapp, 2007. © 2007 Wiley‐Liss, Inc.