
Hand preference and sex shape the architecture of language networks
Author(s) -
Hagmann Patric,
Cammoun Leila,
Martuzzi Roberto,
Maeder Philippe,
Clarke Stephanie,
Thiran JeanPhilippe,
Meuli Reto
Publication year - 2006
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.20224
Subject(s) - hum , right hemisphere , lateralization of brain function , psychology , tractography , left handed , hand preference , preference , laterality , neuroscience , cognitive psychology , magnetic resonance imaging , diffusion mri , medicine , physics , microeconomics , optics , economics , radiology , art , performance art , art history
In right‐handed subjects, language processing relies predominantly on left hemisphere networks, more so in men than in women, and in right‐ versus left‐handers. Using DT‐MRI tractography, we have shown that right‐handed men are massively interconnected between the left‐hemisphere language areas, whereas the homologous in the right hemisphere are sparse; interhemispheric connections between the language areas and their contralateral homologues are relatively strong. Women and left‐handed men have equally strong intrahemispheric connections in both hemispheres, but women have a higher density of interhemispheric connections. Hum Brain Mapp, 2006. © 2006 Wiley‐Liss, Inc.