Open AccessNeural network involved in time perception: An fMRI study comparing long and short interval estimation
Author(s) -
Pouthas Viviane,
George Nathalie,
Poline JeanBaptiste,
Pfeuty Micha,
VandeMoorteele PierreFrançois,
Hugueville Laurent,
Ferrandez AnneMarie,
Lehéricy S.,
LeBihan Denis,
Renault Bernard
Publication year - 2005
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.20126
Subject(s) - neuroscience , anterior cingulate cortex , psychology , time perception , premotor cortex , inferior frontal gyrus , supplementary motor area , basal ganglia , functional magnetic resonance imaging , caudate nucleus , prefrontal cortex , perception , cognition , central nervous system , anatomy , medicine , dorsum
In this study, long (∼1,300 ms) and short duration (∼450 ms) estimation trials in an event‐related functional MRI (fMRI) study were contrasted in order to reveal the regions within a time estimation network yielding increased activation with the increase of the duration to be estimated. In accordance with numerous imaging studies, our results showed that the presupplementary motor area (preSMA), the anterior cingulate, the prefrontal and parietal cortices, and the basal ganglia were involved in the estimation trials whatever the duration to be estimated. Moreover, only a subset of the regions within this distributed cortical and subcortical network yielded increased activation with increasing time, namely, the preSMA, the anterior cingulate cortex, the right inferior frontal gyrus (homolog to Broca's area), the bilateral premotor cortex, and the right caudate nucleus. This suggests that these regions are directly involved in duration estimation. We propose that the caudate‐preSMA circuit, the anterior cingulate, and the premotor‐inferior frontal regions may support a clock mechanism, decision and response‐related processes, and active maintenance of temporal information, respectively. Hum. Brain Mapping, 2005. © 2005 Wiley‐Liss, Inc.