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End‐stae dementia in adults with down syndrome
Author(s) -
Prasher V.
Publication year - 1995
Publication title -
international journal of geriatric psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 129
eISSN - 1099-1166
pISSN - 0885-6230
DOI - 10.1002/gps.930101213
Subject(s) - hypertonia , dementia , personality changes , mood , psychology , severe dementia , personality , disease , medicine , psychiatry , pediatrics , gerontology , social psychology
End‐stage dementia in adults with Down syndrome has not been fully investigated. Available information, 6 months prior to death, for 20 adults with Down syndrome who had died with Alzheimer's disease was reviewed. A terminal stage of severe intellectual deterioration, marked personality and mood changes, loss of sphincter control, seizure activity, immobility with hypertonia and complete loss of self‐care skills was found. These findings have important clinical and service implications.