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Do visuospatial and constructional disturbances differentiate frontal variant of frontotemporal dementia and Alzheimer's disease? An experimental study of a clinical belief
Author(s) -
Grossi Dario,
Fragassi Nina Antonetta,
Chiacchio Laura,
Valoroso Luigi,
Tuccillo Rosaria,
Perrotta Concetta,
Rapone Paola,
Conchiglia Giovanna,
Trojano Luigi
Publication year - 2002
Publication title -
international journal of geriatric psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 129
eISSN - 1099-1166
pISSN - 0885-6230
DOI - 10.1002/gps.654
Subject(s) - frontotemporal dementia , psychology , neuropsychology , dementia , copying , cognition , alzheimer's disease , degenerative disease , cognitive psychology , audiology , disease , developmental psychology , central nervous system disease , psychiatry , neuroscience , medicine , pathology , political science , law
Background In recent years several attempts have been made to distinguish frontotemporal dementia (FTD) from Alzheimer's disease (AD) on neuropsychological grounds; in particular, it has been suggested that FTD patients show spared spatial abilities with respect to AD patients. Objective We aimed at verifying whether patients with the frontal variant of frontotemporal dementia (fv‐FTD) and AD patients perform differently on visuospatial and constructional tasks. Methods We assessed a wide range of visuospatial abilities and provided a qualitative analysis of constructional performances in 14 fv‐FTD patients and 11 AD patients, matched for general cognitive abilities. Results The two groups of patients achieved similar scores on two copying tasks, presented similar drawing procedures in copying Rey complex figure and made a similar quantitative and qualitative pattern of errors in copying simple geometrical drawings. Moreover, no significant difference was found between fv‐FTD and AD patients on a specific battery for visuospatial abilities. Conclusions Our data and a review of the literature suggest that basic visuospatial and constructional skills cannot be taken as a reliable diagnostic criterion for distinguishing fv‐FTD and AD at a mild to moderate disease stage and that the clinical belief of spared spatial abilities in fv‐FTD has to be referred to the lack of topographic disorientation in comparison to AD. Copyright © 2002 John Wiley & Sons, Ltd.