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Obstructive sleep apnoea and dementia: is there a link?
Author(s) -
Shastri Abhishek,
Bangar Santosh,
Holmes John
Publication year - 2016
Publication title -
international journal of geriatric psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 129
eISSN - 1099-1166
pISSN - 0885-6230
DOI - 10.1002/gps.4345
Subject(s) - dementia , cognitive decline , sleep (system call) , cognition , sleep disorder , psychology , narrative review , modalities , medicine , mechanism (biology) , gerontology , psychiatry , disease , intensive care medicine , social science , philosophy , epistemology , sociology , computer science , operating system
Objective Obstructive sleep apnoea is a common sleep disturbance in people of all ages, while dementia is an increasing entity among the ageing population of the world. Recent studies have established a link between sleep apnoea and cognitive decline. This literature review explores this relationship and examines the mechanisms, neurobiology and treatment modalities. Design The study was conducted with the use of narrative literature overview. Results and conclusions While there are numerous studies that establish a clear relationship between obstructive sleep apnoea, cognitive decline and dementia, more work is needed in understanding the mechanism and processes involved. A detailed understanding of pathophysiology of sleep and the relationship with cognitive decline will be vital in addressing the possibility of averting a likely reversible cause of dementia or cognitive decline. Copyright © 2015 John Wiley & Sons, Ltd.